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KMID : 0352819890050020037
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Kosin Medical Journal
1989 Volume.5 No. 2 p.37 ~ p.54
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Thyroid Lesions among Koreans
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천봉권/Chun, Bong Kwon
장희경/허방/허만하/Chang, Hee Kyung/Hur, Bang/Huh, Man Ha
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Abstract
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A total of 560 cases of surgically resected thyroid specimens from the pathology files of Department of Pathology, Kosin Medical Center, during the period of 18 years from 1971 to 1988, was pathologically reevaluated.
These thyroid lesions consisted of thyroiditis, goiter, adenoma, thyroid malignancy, and other miscellaneous diseases. Histopathological classifications of all thyroid lesions were based on Volpe´s classification for thyroiditis, Robbins´ for goiter, Rosai´s for adenoma, and Meissner´s for thyroid malignancy. This study was performed to elucidate the relative frequency of the thyroid diseases on the basis of morphological alterations and to compare the results with the previous studies in Korea and other counturies. Also pathological observations were per-formed with special reference to the lymphocytic reaction in connection with the thryoid malignancy and the formation of calcific bodies in association with papillary neoplasms.
The 560 cases were classified pathologically into 29 acute and chronic thyroiditis(5.2%), 160 goiter(28.5%), 177 adenoma(31.6%), and 187 thyroid malignancy(33.4%). Hashimoto´s thyroiditis was the commonest thyroiditis(17 cases), rep-
resenting 58.7% of all thyi,,,4itis. Nontoxic goiter occupied 93.8% of all the goiter, and nontoxic nodular goier represented 91.2% of all the goiter. Adenomas consisted of 171 follicular type(86.6%), 3 Hurthle cell adenoma, and 3 atypical adenoma. Histopathologically, 114 papillary carcinoma represented 77.0% of all the thyroid malignancy. All the carcinoma in teenagers(6 cases) showed papillary growth. No relationship between the types of thyroid carcinoma and the frequency of lymphocytic infiltration was seen. Of 144 papillary carcinoma, 30 cases showed calcification in the neoplastic tissue. The relatively higher proportion of thyroid maligancy ´ in this report, compared with the previous reports in Korea and other counturies, is probably related to the nature of this medical institute.
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KEYWORD
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